Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_727	Vaccinia virus	VV-Onco	DNA	Poxviridae	The viral thymidine kinase (TK) gene is insertionally inactivated	Yes	No	No	Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China	Human hepatocellular carcinoma cell line	MHCC97-H	5000 to 7000 cells per well	NA	MTT assay	1 MOI	70% cancer cell viability at 96 hours post-infection	No	No	NA	No response	NA	NA	NA	NA	27441866
OV_728	Vaccinia virus	VV-Onco	DNA	Poxviridae	The viral thymidine kinase (TK) gene is insertionally inactivated	Yes	No	No	Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China	Human hepatocellular carcinoma cell line	MHCC97-H	5000 to 7000 cells per well	NA	MTT assay	10 MOI	50% cancer cell viability at 96 hours post-infection	No	No	NA	No response	NA	NA	NA	NA	27441866
OV_729	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	10 MOI	97% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_730	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	10 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_731	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	50 MOI	52% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_732	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	50 MOI	50% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_733	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	100 MOI	33% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_734	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	100 MOI	38% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_735	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_736	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_737	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	50 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_738	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	MTT assay	50 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_739	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	100 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_740	Adenovirus	AdTrack	DNA	Adenoviridae	None	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	MTT assay	100 MOI	100% cancer cell viability on day 5	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_741	Adenovirus	AdAFPp-E1A-122	DNA	Adenoviridae	The viral insertion mutant with miR-122 target sequence into AdAFPp-E1A for negatively regulating E1A gene expression	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with mimics	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	50 MOI	80% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_742	Adenovirus	AdAFPp-E1A-122	DNA	Adenoviridae	The viral insertion mutant with miR-122 target sequence into AdAFPp-E1A for negatively regulating E1A gene expression	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with negative control	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	50 MOI	50% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_743	Adenovirus	AdAFPp-E1A-122	DNA	Adenoviridae	The viral insertion mutant with miR-122 target sequence into AdAFPp-E1A for negatively regulating E1A gene expression	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with mimics	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	100 MOI	65% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_744	Adenovirus	AdAFPp-E1A-122	DNA	Adenoviridae	The viral insertion mutant with miR-122 target sequence into AdAFPp-E1A for negatively regulating E1A gene expression	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with negative control	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	100 MOI	45% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_745	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with mimics	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	50 MOI	61% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_746	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with negative control	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	50 MOI	61% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_747	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with mimics	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	100 MOI	46% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_748	Adenovirus	AdAFPp-E1A	DNA	Adenoviridae	The viral mutant with E1A gene driven by AFP promoter	Yes	No	No	Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, and Peking Union Medical College (PUMC), Tianjin, China	Human hepatocellular carcinoma cell line	HepG2 with negative control	1.0E+4 cells per well	Slight toxicity to HL-7702 cell line	MTT assay	100 MOI	46% cancer cell viability on day 3	No	No	NA	No response	NA	NA	NA	NA	27450327
OV_856	Adenovirus	CV890	DNA	Adenoviridae	E1A and E1B gene under control of Adenovirus promoter	No	Virus strain in combination with Doxorubicin (10ng/ml)	No	ATCC	Human hepatoma cell line	Hep3B	NA	NA	MTT assay	0.01pfu/cell	90% cancer cell killing after day 9, showing synergism with drug	No	No	NA	No response	NA	NA	NA	NA	11522637
OV_857	Adenovirus	CV890	DNA	Adenoviridae	E1A and E1B gene under control of Adenovirus promoter	Yes	No	No	ATCC	Human hepatoma cell line	Hep3B	NA	NA	MTT assay	0.01pfu/cell	35% cancer cell killing after day 9	No	No	NA	No response	NA	NA	NA	NA	11522637
OV_1315	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	0.01 MOI	some cells are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1316	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	0.1 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1317	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	1 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1318	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	10 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1319	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	100 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1320	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	0.01 MOI	some cells are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1321	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	0.1 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1322	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	1 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1323	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	10 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1324	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	100 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1325	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	0.01 MOI	some cells are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1326	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	0.1 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1327	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	1 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1328	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	10 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1329	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	100 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1330	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	0.01 MOI	Some cell are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1331	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	0.1 MOI	Some cell are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1332	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1333	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	10 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1334	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	100 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1335	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	0.01 MOI	Some cell are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1336	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	0.1 MOI	Some cell are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1337	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1338	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	10 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1339	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	100 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1340	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	0.01 MOI	Some cell are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1341	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	0.1 MOI	Some cell are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1342	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1343	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	10 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1344	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	100 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1345	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	100MOI	50% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1346	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	100MOI	50% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1347	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	100MOI	30% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1348	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	SMMC7721	NA	NA	Crystal violet staining	100MOI	30% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1349	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	SMMC7721	NA	NA	Crystal violet staining	100MOI	30% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1350	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	SMMC7721	NA	NA	Crystal violet staining	100MOI	30% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_2047	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	0.1 MOI	50% cell survival after 24 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2048	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	0.1 MOI	20% cell survival after 48 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2049	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	0.1 MOI	20% cell survival after 72 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2050	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	0.1 MOI	22% cell survival after 96 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2051	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	1 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2052	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	1 MOI	58% cell survival after 48 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2053	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	1 MOI	30% cell survial after 72 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2054	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	1 MOI	22% cell survival after 96 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2055	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	0.1 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2056	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	0.1 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2057	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	0.1 MOI	30% cell survival after 72 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2058	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	0.1 MOI	30% cell survival after 96 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2059	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	1 MOI	80% cell survival after 24 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2060	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	1 MOI	30% cell survival after 48 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2061	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	1 MOI	20% cell survival after 72 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2062	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	1 MOI	20% cell survival after 96 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2063	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	NA	NA	NA	Athymic hsd nude mice xenograft for PLC cell line	5.0E+6 pfu	Reduction in tumor volume below 2000mm compared to control after 45 days	No response	NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2064	Vaccinia virus	GLV-1h68	DNA	Poxviridae	None	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	NA	NA	NA	Athymic hsd nude mice xenograft for PLC cell line	5.0E+6 pfu	Reduction in tumor volume below 3000mm compared to control after 35 days		NA	Induction of apoptosis in cancer cell line	Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2	NA	21779374
OV_2094	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MRC-5	NA	NA	Crystal violet staining	0.1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2095	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MRC-5	NA	NA	Crystal violet staining	1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2096	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MRC-5	NA	NA	Crystal violet staining	10 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2097	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MRC-5	NA	NA	Crystal violet staining	100 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2098	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	0.1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2099	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2100	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	10 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2101	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	100 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2110	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2111	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2112	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2113	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	100 MOI	Most of the cells are died	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2114	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2115	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2116	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	10 MOI	Most of the cells are died	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2117	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	100 MOI	Most of the cells are died	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2118	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	0.1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2119	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2120	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	10 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2121	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	100 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2130	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2131	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578

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